"The United States will meet our emissions targets," he said, laying out major legislation passed under his presidency, including the largest ever US government investment in clean energy.
Biden, who was spending only a few hours in the resort of Sharm El Sheikh before travelling on to ASEAN and G20 summits in Asia, challenged other countries to do more to cut carbon emissions in the hope of bringing global warming under control.
"Every nation needs to step up. At this gathering, we must renew and raise our climate ambitions," he said in a speech that lasted about 22 minutes and was briefly interrupted by unidentified people in the crowd making howling noises.
"It's a duty and responsiblity of global leadership. Countries that are in a position to help should be supporting developing countries so they can make decisive climate decisions -- facilitating their energy transitions, building a path to prosperity compatible with our climate imperative."
In a pointed criticism of the upheaval sparked by Russia's invasion of Ukraine, Biden said the conflict gave fresh impetus to the ongoing push to replace oil and gas with renewable sources. As a major energy exporter, Moscow has for years had a strong economic grip on energy poor western Europe.
"Russia's war only enhances the urgency of the need to transition the world off its dependence on fossil fuels," Biden said.
As he left the venue to return to Air Force One for the flight to the regional ASEAN summit in Cambodia, reporters asked Biden what would persuade his Republican party opponents to agree to fund expensive climate initiatives.